What type of person is most likely to benefit from weight-loss drugs?
Doctors may prescribe weight-loss medication if you are unable to shed the pounds through a healthy diet and exercise regimen and meet one of the following conditions: More than 30% of the population has a BMI over 30. Your BMI is at least 27 and you have a serious obesity-related medical condition, such as diabetes or high blood pressure. Before making a medicine recommendation, your doctor will look through your medical history and current health issues. After that, your doctor will go over the advantages and disadvantages of weight loss medicines with you. It's critical to remember that not everyone can benefit from weight-loss medications. The use of certain weight-loss medications while you are trying to conceive, pregnant or nursing should be avoided at all costs.
Do Diet Pills Really Work to Lose Weight?
Weight reduction tablets prescribed for long-term use (more than 12 weeks) result in significant weight loss when compared to a placebo. Weight loss medicines and lifestyle changes work better together than they do on their own.
Over the course of a year, you might lose 3% to 7% of your body weight, which is a lot more than simply making lifestyle changes. This may seem like a small amount. Losing 5 to 10 percent of one's body weight over time, on the other hand, can have significant health advantages, such as lowering blood pressure, blood glucose, and cholesterol.
Multiple gastrointestinal disorders can be helped by the medication linaclotide (brand name: LINACLOTIDE) (irritable bowel syndrome with constipation, chronic idiopathic constipation). It helps digestion by increasing the amount of fluid in the intestines. In addition to alleviating symptoms like bloating, abdominal pain or discomfort, tension, and the feeling that bowel motions are incomplete, linaclotide may also assist to improve colon structure.
How To Use?
Before you begin taking linaclotide and each time you renew your prescription, read the prescription information issued by your pharmacist. Contact your doctor or pharmacist if you have any concerns. As directed by your doctor, take this medication once a day on an empty stomach, at least 30 minutes before your first meal. Capsules should be ingested in their whole body. The pill should not be broken open or chewed. If you have difficulty swallowing the capsule's contents, open the capsule and mix them with a teaspoon of apple sauce. Swallow the mixture whole, without chewing it first.
Avoid keeping the mixture for subsequent use. Alternatively, 30 mL of water can be used to dilute the contents of the capsule's capsules. Take a sip of the mixture without chewing after swirling it for 20 seconds. Pour in 30 ml (1 ounce) of water, mix for 20 seconds, then drink immediately away to obtain the whole dose. A tube can be used to inject the watery solution directly into the stomach (nasogastric orogastric tube). Ask your healthcare practitioner for detailed advice on how to deliver this medication if you are using a tube.
It is possible to experience symptoms such as constipation, diarrhea, gas, bloating, and/or stomach pain. Inform your doctor or pharmacist as soon as possible if any of these adverse effects continue or become more severe.
Because your doctor believes that the benefits of this drug outweigh the risks to your health, he has recommended that you take it. The vast majority of people who use this medicine do not experience any significant negative side effects at all.
If you experience any of the following side effects, you should discontinue use of this medication immediately.
An acute episode of diarrhea has occurred.
There is a low likelihood that this medication can cause serious allergic reactions. Among the symptoms of a severe allergic reaction that may necessitate immediate medical attention are, but are not limited to, the following:
The most common symptoms include swelling of the face, tongue, or throat, as well as itching. Diarrhea and dizziness are common side effects. Anxiety over taking a breath
Linaclotide has the potential to produce adverse effects, so inform your doctor or pharmacist if you have any extra sensitivities before starting treatment with this medication. The inactive compounds in this product have the potential to cause allergic responses or other problems in some people. Speak with your pharmacist if you require any additional information.
Prior to using this drug, you should consult with your doctor or pharmacist about your medical history, particularly if you have any of the following conditions: a stumbling block in the digestive tract Consult with your doctor or dentist before undergoing any procedure to ensure that they are aware of any drugs or treatments you are currently receiving (including prescription medications, non-prescription medications, and herbal products).
Use is contraindicated in certain situations.
If you take more than one medicine at the same time, you may be at greater risk of experiencing serious adverse effects. It is not possible to include all conceivable medication interactions in this publication due to space constraints. Be sure to keep note of all of the medications and supplements you take (both prescription and over-the-counter), and to share this information with your physician and pharmacist as necessary. Changing or discontinuing any medicine you are currently taking should only be done with the approval of your doctor.
This medicine may have an interaction with the following medications:
This product should be stored at room temperature in its original container, away from direct sunlight and moisture. It should not be frozen. A properly closed container will aid in the preservation of the desiccant's moisture content. The bathroom is strictly prohibited. Children and dogs should not have access to any medications, therefore keep them out of reach of children and pets.
Do not flush or pour the medication down the toilet unless specifically instructed to do so by your doctor. When a product is no longer needed or has expired, it should be disposed of correctly to avoid contamination. Consult with a pharmacist or a garbage disposal company in your area if you require further assistance.
In a breakthrough discovery, researchers at the Biomedical Research Network Center for the Physiopathology of Obesity and Nutrition (CIBEROBN) demonstrate the effectiveness of linaclotide, a drug that is currently available for the treatment of intestinal disease, in the treatment of obesity. This medication promotes the fat membrane by increasing the amount of energy expended. As a result, weight loss occurs without the need to reduce caloric intake.
Using experimental animals, this research group, led by Luisa Mara Seoane from Santiago de Compostela, has demonstrated that oral administration of this compound increases brown fat (also known as good fat), increases energy expenditure, and causes weight loss, which is followed by fatigue and constant tiredness.